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The Catalytic Framework to End AIDS, TB and Eliminate Malaria in Africa by 2030

With the significant progress made and the remaining challenges that can put the continent off track in responding to the three biggest diseases on the continent, the Catalytic Framework to end AIDS, TB and Eliminate Malaria in Africa by 2030 provides a business model for investing for impact. The framework emphasises the need for each country to place a specific focus on increasing domestic health financing. It underscores the need to ensure that available resources should be invested and targeted where the disease burden is highest. The framework focusses on three strategic investment areas, each with clear catalytic actions. These areas are health systems strengthening, generation and use of evidence for policy and programme interventions and advocacy and capacity building. The framework provides clear targets and milestones for ending the three diseases by 2030.

The objective of the Catalytic Framework is to intensify the implementation of the Abuja +12 commitments by building Africa-wide consensus on the key strategic actions within the context of the existing targets and milestones.The Catalytic Framework is aligned with the set goals and targets in the Sustainable Development Goals (SDGs) and AU Agenda 2063. These reflect the interdependence and complexity of a changing world, and the imperative for global collective action. By shifting from development for the poorest countries to sustainable development for all, the global agenda has expanded its scope. As a set of indivisible goals, the SDGs provide all stakeholders with a mandate for integration of efforts. The Catalytic Framework places the vulnerable populations at the centre of the proposed accelerated actions towards sustainable development.

The Agenda 2063 framework adopted by the African Union Assembly in 2015, guides the continent towards a common focus in the developmental and political evolutionary process for Africa’s growth. Agenda 2063 articulates the AU’s 50-year vision and is based on seven aspirations derived from extensive continental consultations. These are (1) a prosperous Africa based on inclusive growth and sustainable development; (2) an integrated continent, politically united, based on the ideals of Pan Africanism and the vision of Africa’s Renaissance; (3) An Africa of good governance, respect for human rights, justice and the rule of law; (4) a peaceful and secure Africa (5) An Africa with a strong cultural identity, common heritage, values and ethics; (6) an Africa whose development is people-driven, relying on the potential of African people, especially its women and youth, and caring for children; and (7) Africa as a strong, united, resilient and influential global player and partner. The health track is embedded in the first aspiration under goal 3- healthy and well-nourished citizens. Africa’s development framework, Agenda 2063 includes the following health targets- access to quality basic health care and services; maternal, neo-natal and child mortality rates; HIV/AIDS, malaria and TB; child stunting and malnutrition; Africa Centres for Disease Control; African Medicines Regulatory Harmonisation and domestic financing for health.


Africa free of AIDS, tuberculosis and malaria

Overall Goal

To end AIDS and tuberculosis and eliminate malaria in Africa by 2030


  • To eliminate malaria incidence and mortality, prevent its transmission and re-establishment in all countries by 2030;
  • To end the AIDS as a public health threat by 2030;
  • To end TB deaths and cases by 2030.

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